One of the most significant natural features in Missouri, Greer Spring, is the second largest spring in Missouri with a mean daily discharge of approximately 210 million gallons/day. It also has the longest spring branch of all the first magnitude springs in the state, flowing just over a mile before entering the Eleven Point River. This is a state and nationally significant geologic feature of a phreatic spring. In addition to the geologic significance of Greer Spring, it is a significant aquatic natural community supporting a diverse assemblage of native fish species and aquatic invertebrates, including some species of conservation concern such as the coldwater crayfish (Faxonius eupunctus). The flora of the spring branch and associated Ozark fens is diverse as well. Greer Spring is critically important to the hydrology of the Eleven Point River, a National Wild and Scenic River.
About one mile south of the Highway 19 crossing of the Eleven Point River look for the area parking lot and trailhead on the west side of Highway 19. A one-mile long (one-way) trail leads down to the spring.