The Spring River Basin is located in southwest Missouri in Barry, Barton, Christian, Dade, Jasper, Lawrence, Newton, and Stone counties. The basin lies along the border between the Osage Plains and Springfield Plateau physiographic regions. The Spring River originates along the Barry-Lawrence county line south of Verona, flows west-northeast to its confluence with the North Fork of the Spring River east of Asbury in Jasper County and then southwest into Kansas and Grand Lake of the Cherokees in Oklahoma. Major tributaries within the basin are the North Fork of the Spring River, Center Creek, Turkey Creek, and Shoal Creek. Numerous smaller tributaries flow throughout the basin.