The Eleven Point River originates near the town of Willow Springs, located in northeastern Howell County. The river flows southeasterly across northern Howell and Oregon Counties and then south, crossing the Arkansas state line about 2.5 miles west of the southeast corner of Oregon County. From there it flows generally south through Randolph County, Arkansas, joining the Spring River approximately 3.7 miles above the Spring River/Black River Confluence near Black Rock, Arkansas. The Black River is a tributary of the White River. Major tributaries of the Eleven Point River include Middle Fork, Spring Creek, Hurricane Creek, and Fredrick Creek. Greer Spring also contributes significantly to the flow of the Eleven Point River, turning the river into a cold water stream.